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	<title>mathewingram.com/work &#187; genome</title>
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		<title>Viruses and hacking the human genome</title>
		<link>http://www.mathewingram.com/work/2007/12/24/viruses-and-hacking-the-human-genome/</link>
		<comments>http://www.mathewingram.com/work/2007/12/24/viruses-and-hacking-the-human-genome/#comments</comments>
		<pubDate>Tue, 25 Dec 2007 00:02:07 +0000</pubDate>
		<dc:creator>Mathew</dc:creator>
				<category><![CDATA[Cool]]></category>
		<category><![CDATA[genome]]></category>
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		<category><![CDATA[virus]]></category>

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		<description><![CDATA[Via my friend Rob Hyndman (who came across it via David &#8220;Joho the Blog&#8221; Weinberger), I just finished reading a fascinating article in The New Yorker about how HIV-style &#8220;retroviruses&#8221; from millions of years ago have successively rewritten the human genome, and may have even been instrumental in reprogramming our DNA in ways that helped [...]]]></description>
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<p>Via my friend Rob Hyndman (who came across it <a href="http://www.hyperorg.com/blogger/2007/12/24/viruses-as-evolutions-sculptor/">via</a> David &#8220;Joho the Blog&#8221; Weinberger), I just finished reading a <a href="http://www.newyorker.com/reporting/2007/12/03/071203fa_fact_specter?printable=true">fascinating article</a> in The New Yorker about how HIV-style &#8220;retroviruses&#8221; from millions of years ago have successively rewritten the human genome, and may have even been instrumental in reprogramming our DNA in ways that helped the human race to survive &#8212; for example, by causing proto-humans to develop the ability to give birth to their young alive.</p>
<p>One of the disturbing aspects of the article (at least to me) was the description of how researchers had recreated, Jurassic Park style, a virus that existed hundreds of thousands of years ago, and how:</p>
<blockquote><p>&#8220;Thanks to steady advances in computing power and DNA technology, a talented undergraduate with a decent laptop and access to any university biology lab can assemble a virus with ease.&#8221;</p></blockquote>
<p>Kind of a disturbing image: a medical hacker with some mail-order biological material and a virus database, working away in some basement lab. I realize there have been movies and books about this concept, but it always seemed like science fiction. Now it seems a lot more like just plain science. But even apart from that kind of movie-of-the-week idea, I think it&#8217;s fascinating that horrible epidemics in the past may have <a href="http://www.newyorker.com/reporting/2007/12/03/071203fa_fact_specter?printable=true">helped create</a> the human race as we know it.</p>
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